By : M. Lieberman
Multiple Sclerosis is a disease of the central nervous system in
which patches of myelin and underlying nerve fibers are damaged or
destroyed. Over time, the condition gets worse and the individual
experiences both a loss of feeling and loss of control of movement and
speech.
It poses a serious threat to the individual's
brain, spinal cord and or optic nerves. Multiple Sclerosis destroys the
myelin sheath, which are layers of tissue that protect the nerve fibers.
Myelin aids in nerve cell communication. As this deterioration happens,
it becomes noticeable in the individual's behavior, going from normal
to abnormal. Multiple Sclerosis can both progress and regress
unpredictably.
The actual cause of Multiple Sclerosis is unknown,
but it is thought that either a virus or some unknown antigen somehow
triggers a reaction that is directed against the body's own tissues and
this usually occurs early in life. The autoimmune reaction results in
the inflammation, destruction of myelin and significant damage to the
myelin sheath and the underlying nerve fibers.
In adults, the myelin sheath can be damaged or
destroyed by stroke, inflammation, immune disease, metabolic disorders
and any of the various nutritional deficiencies. Poisons and the
excessive use of alcohol can also damage and destroy the myelin sheath.
If the sheath is able to repair itself and regenerate, there is a
possibility for normal nerve function to return. If the sheath is
severely damaged, the underlying nerve fiber can die and this results in
irreversible damage.
Disorders of the central nervous system (brain and
spinal cord) that cause demyelination and have no known cause are
referred to as primary demyelinating disorders. Multiple Sclerosis
happens to be the most common of these disorders.
Some of the contributing facts associated with Multiple Sclerosis include heredity and environment.
- If the gene is present, this greatly contributes to your risk of
developing the disease at any stage of life. Children are at risk, if
either parent has a history of the disease.
- Environment also has a role. Temperate and tropical climates
have a major effect. Where individuals spend the first 15 years of their
life, affects the chances of developing the disease.
As Multiple Sclerosis begins affecting the nervous
system, the individual can experience tingling, numbness, pain, burning
and itching in the arms, legs, trunk or face and the loss of strength or
dexterity in a leg or hand. The person can feel unusually tired; have
mood swings, euphoria and depression. Also possible are memory
disturbances, decreased judgment and inattention.
Because the symptoms of Multiple Sclerosis vary
widely, doctors may not be able to recognize the disorder in the
earliest stages. When the disease is suspected, a thorough examination
of the nervous system is performed during the physical examination.
Although there is no single diagnostic test, laboratory tests can help
distinguish Multiple Sclerosis from other disorders that can produce
similar symptoms, such as AIDs, ALS, Lupus and Lyme disease. A spinal
tap may be ordered to check both the white blood cell count and protein
content in the fluid, paying special attention to the concentration of
antibodies. There is evidence that a specific pattern of antibodies is
detected in the majority of people with the disease. MRI's are the best
imaging procedure for detecting and confirming the diagnosis.
A procedure that involves evoked responses may be
performed. In these tests, certain types of sensory stimuli are used to
activate certain areas of the brain and the brain's responses are
recorded. In a person who has the disease, the brain's response to the
actual stimuli maybe very slow, because the signal conduction along the
damaged nerve fibers is impaired. This procedure also helps detect if
there is damage to the optic nerve.
There is no treatment for Multiple Sclerosis that
is uniformly effective. There are numerous medications that are used in
the treatment, such as corticosteroids, but many of the drugs are
administered with the hope of controlling the various symptoms. The
benefits of using a procedure called plasmapheresis have not been
established as yet, but many of the experts recommend it to prevent
severe relapses, that are not controlled by the use of corticosteroids.
Plasmapheresis involves the removal of blood, so that abnormal
antibodies can be removed and then the purified blood is returned to the
person.
People with this disease can often maintain an
active lifestyle, until they conditions gets worse, which is over time.
They may become tired very easily and not be able to keep up with a
demanding lifestyle. Light exercise and physical therapy can help
maintain cardiovascular, muscular and psychological health.
Participating in a physical therapy program can help with maintain
balance, walking ability and range of motion.
- The single most important thing you can do is to maintain a proper diet to strengthen your immune system.
- Avoid the excessive consumption of alcohol.
- If you have any other illnesses or disease conditions, you must
make your doctor aware of them, so that any medications you might be put
on with not have adverse side effects.
- If you feel that you are experiencing any of the symptoms of
Multiple Sclerosis, it is imperative that you see your doctor as soon as
possible.
- If you are a teen or young adult and either of your parents has
the disease, you must advise your doctor of this and be monitored on a
regular basis.
- If you are planning a trip to another state or a foreign
country, find out if the change in environment could cause you any types
of problems.